作者: Katie L Druce , Neil Basu
DOI: 10.1093/RHEUMATOLOGY/KEZ346
关键词:
摘要: People with RA commonly experience fatigue. Fatigue is a key contributor to increased clinical care costs, primary consultations and employment loss. Despite this, our understanding of the prognostic factors poor fatigue outcomes lacking poorly managed. Examining longitudinal predictors can identify both individuals 'at risk' prognosis, candidate mechanisms that are worthy greater inspection. This review discusses most investigated as being implicated in prognosis The available data appears implicate generic such pain, mental health, disability sleep consistent outcome, while role disease activity inflammation seems less clear. However, existing not without methodological limitations there have been no specific studies primarily designed investigate inflammatory biomarkers Future required more comprehensively robustly determine