Prognostic significance of serum inflammatory response markers in newly diagnosed non-small cell lung cancer before chemoirradiation
作者： Maria Tolia , Nikolaos Tsoukalas , George Kyrgias , Eftychia Mosa , Apostolos Maras
DOI: 10.1155/2015/485732
关键词:
摘要: Purpose. To identify whether the serum’s baseline C-reactive protein (CRP) and albumin (Alb) levels related to clinicopathological parameters overall survival (OS) in non-small cell lung cancer (NSCLC). Methods. In total, 100 consecutive patients (mean age = 68.38 ± 10.85 years) that underwent chemoradiotherapy were studied. Measurements of CRP Alb performed before any treatment. Results. Serum significantly associated with histological grade , TNM stage PS . Additionally found univariate analysis (log-rank test, resp.) remained significant after controlling for age, alcohol, performance status, stage, whereas showed a borderline effect on hazard rate Conclusions. are both promising biomarkers identification NSCLC poor prognosis form possible target intensifying their therapies.
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