Changes of acute-phase protein levels in the serum of lung cancer patients following radiotherapy.

作者: Tolia G Maria , Kouloulias E Vasileios , Pantelakos S Panagiotis , Syrigos N Kostas , None

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摘要: Purpose: the assessment of serum level changes C-reactive protein (CRP), ferritin (FER), and albumin (ALB) as inflammation markers in Non Small Cell Lung Cancer patients (stages IIIA - inoperable stage IIIB) treated with radiotherapy. Significant findings: Normal pre-radiotherapy levels CRP were found 18 patients, FER 17, ALB 22. Higher 9 10. Lower was 5 patients.Post-radiotherapy significantly higher (compared to levels) 25 patients. The same observed regarding whereas 12 had lower post-radiotherapy levels. statistical analysis (non parametrical Wilcoxon test) revealed that these differences statistically significant (p-value< 0.001). Conclusions: CRP, FER, are reliable useful biomarkers correlated acute complication lung parenchyma damage induced by

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