A comparative MR and pathological study on fetal CNS disorders

摘要: Object: We used MR after sonography to help us in prenatal counseling 58 complicated pregnancies from 1998 2000. Methods: All fetal examinations were undertaken with a 1.5-T magnet using body-phased-array coil and an ultrafast imaging technique, half-Fourier single-shot turbo spin-echo (HASTE). Twelve fetuses found have major anomalies, each of these cases either delivery was induced or the pregnancy terminated. In 6 fetuses, anomalies central nervous system, postmortem then performed they failed survive, constitute patient sample investigated current study. The gestational ages ranged 24 32 weeks. demonstrated morphological details anomalies. They were: alobar holoprosencephaly 2, middle interhemispheric fusion 1, Dandy-Walker malformations variant 1 twin-twin transfusion syndrome hypoxic-ischemic injury brain 1. Conclusions: Postmortem confirmed diagnoses, observations support improving our understanding pathogenesis CNS