Diagnosis and management of nocturnal enuresis.

摘要: Purpose of review To highlight recent advances in enuresis research. Recent findings Many discoveries have distanced us from the time when bedwetting was considered a psychiatric disorder. Instead, it is now agreed that nocturnal polyuria, detrusor overactivity, and high arousal thresholds are, various combinations, central to pathogenesis. All three mechanisms been further elucidated during last year. It has found solute diuresis, not just free-water diuresis due vasopressin deficiency, may be causative. Sonographical bladder wall measurements shown prognostic value detrusor-dependent enuresis, fascinating proof for interplay between sleeping brain put forward. And, ironically, sleep research caused psychiatry make slight comeback, as studies indicated enuretic children suffer cognitive problems suboptimal sleep. Less achieved regarding treatment, but some evidence finally supported experience anticholinergics effective therapy-resistant enuresis. Summary During years, increased insight gained into multifaceted pathogenesis there still an irritating lack proven therapies.