Recent translational research: stem cells as the roots of breast cancer.

作者: Chia-Cheng Chang

DOI: 10.1186/BCR1385

关键词:

摘要: Common phenotypes of cancer and stem cells suggest that breast cancers arise from cells. Breast epithelial with cell have been shown to be more susceptible immortalization neoplastic transformation. tumor CD44+/CD24-/lowLineage- markers isolated. The role these in progression clinical outcome is not clear. relationship between may elucidated by further studies carcinogenesis nonadherent mammosphere features derivation CD44+/CD24-/low an adherent type.

参考文章(24)
Suling Liu, Gabriela Dontu, Max S Wicha, Mammary stem cells, self-renewal pathways, and carcinogenesis Breast Cancer Research. ,vol. 7, pp. 86- 95 ,(2005) , 10.1186/BCR1021
Ruth Sager, Anthony Anisowicz, Mark Neveu, Peng Liang, Georgia Sotiropoulou, Identification by differential display of alpha 6 integrin as a candidate tumor suppressor gene. The FASEB Journal. ,vol. 7, pp. 964- 970 ,(1993) , 10.1096/FASEBJ.7.10.8344495
Samuel Weiss, Brent A. Reynolds, Angelo L. Vescovi, Cindi Morshead, Constance G. Craig, Derek van der Kooy, Is there a neural stem cell in the mammalian forebrain Trends in Neurosciences. ,vol. 19, pp. 387- 393 ,(1996) , 10.1016/S0166-2236(96)10035-7
Z Zou, A Anisowicz, M. Hendrix, A Thor, M Neveu, S Sheng, K Rafidi, E Seftor, R Sager, Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells Science. ,vol. 263, pp. 526- 529 ,(1994) , 10.1126/SCIENCE.8290962
James E Trosko, CHIA‐CHENG CHANG, Brad L Upham, MEI‐HU TAI, Ignored Hallmarks of Carcinogenesis: Stem Cells and Cell‐Cell Communication Annals of the New York Academy of Sciences. ,vol. 1028, pp. 192- 201 ,(2004) , 10.1196/ANNALS.1322.023
M. Al-Hajj, M. S. Wicha, A. Benito-Hernandez, S. J. Morrison, M. F. Clarke, Prospective identification of tumorigenic breast cancer cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 3983- 3988 ,(2003) , 10.1073/PNAS.0530291100
Desmond E. Thompson, Kiyohiko Mabuchi, Elaine Ron, Midori Soda, Masayoshi Tokunaga, Sachio Ochikubo, Sumio Sugimoto, Takayoshi Ikeda, Masayuki Terasaki, Shizue Izumi, Dale L. Preston, Cancer incidence in atomic bomb survivors. Part II: Solid tumors, 1958-1987. Radiation Research. ,vol. 137, pp. 17- 67 ,(1994) , 10.2307/3578892
Douglas Hanahan, Robert A Weinberg, The hallmarks of cancer. Cell. ,vol. 100, pp. 57- 70 ,(2000) , 10.1016/S0092-8674(00)81683-9
Y. Li, B. Welm, K. Podsypanina, S. Huang, M. Chamorro, X. Zhang, T. Rowlands, M. Egeblad, P. Cowin, Z. Werb, L. K. Tan, J. M. Rosen, H. E. Varmus, Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 15853- 15858 ,(2003) , 10.1073/PNAS.2136825100
Kristin J Hope, Liqing Jin, John E Dick, Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nature Immunology. ,vol. 5, pp. 738- 743 ,(2004) , 10.1038/NI1080