Urinary Free Cortisol Is Unrelated to Physiological Changes in Urine Volume in Healthy Women

作者: Pietro Putignano , Antonella Dubini , Francesco Cavagnini

DOI: 10.1093/CLINCHEM/46.6.879

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摘要: Urinary free cortisol is largely accepted as an accurate means of assessing daily secretion. A more precise definition this marker should be “urinary corticoids” (UFCs), because all competitive binding assays overestimate in urine (1). Recently, it has been argued that volume may a confounding factor high fluid intake reported to significantly increase UFCs healthy subjects (2), and earlier study also stated UFC concentrations are closely related changes children (3). Conversely, recent published Clinical Chemistry …

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