High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides

作者: B. Yang , X. Ming , C. Cao , B. Laing , A. Yuan

DOI: 10.1093/NAR/GKV060

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摘要: … the therapeutic potential of antisense oligonucleotides (ASO)… a threshold effect for oligonucleotide release rather than a … compounds could cause release of oligonucleotide to the …

参考文章(70)
Md. Rowshon Alam, Xin Ming, Michael Fisher, Jeremy G. Lackey, Kallanthottathil G. Rajeev, Muthiah Manoharan, Rudy L. Juliano, Multivalent Cyclic RGD Conjugates for Targeted Delivery of Small Interfering RNA Bioconjugate Chemistry. ,vol. 22, pp. 1673- 1681 ,(2011) , 10.1021/BC200235Q
Patrick Midoux, Chantal Pichon, Jean-Jacques Yaouanc, Paul-Alain Jaffrès, Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers British Journal of Pharmacology. ,vol. 157, pp. 166- 178 ,(2009) , 10.1111/J.1476-5381.2009.00288.X
Vadim Zinchuk, Olga Grossenbacher‐Zinchuk, Quantitative colocalization analysis of confocal fluorescence microscopy images. Current protocols in pharmacology. ,vol. 52, pp. 1- 4 ,(2008) , 10.1002/0471143030.CB0419S52
Vladimir Torchilin, siRNA delivery: from basics to therapeutic applications. Frontiers in Bioscience. ,vol. 18, pp. 58- 79 ,(2013) , 10.2741/4087
Jing Li, Yan Wang, Yu Zhu, David Oupický, Recent advances in delivery of drug-nucleic acid combinations for cancer treatment. Journal of Controlled Release. ,vol. 172, pp. 589- 600 ,(2013) , 10.1016/J.JCONREL.2013.04.010
Ludger Johannes, Christian Wunder, Retrograde transport: two (or more) roads diverged in an endosomal tree? Traffic. ,vol. 12, pp. 956- 962 ,(2011) , 10.1111/J.1600-0854.2011.01200.X
Kathryn A. Whitehead, Robert Langer, Daniel G. Anderson, Knocking down barriers: advances in siRNA delivery Nature Reviews Drug Discovery. ,vol. 8, pp. 129- 138 ,(2009) , 10.1038/NRD2742
Jun Li, Leaf Huang, Targeted delivery of RNAi therapeutics for cancer therapy Nanomedicine: Nanotechnology, Biology and Medicine. ,vol. 5, pp. 1483- 1486 ,(2010) , 10.2217/NNM.10.124
Sébastien Deshayes, Karidia Konate, Anna Rydström, Laurence Crombez, Cédric Godefroy, Pierre-Emmanuel Milhiet, Annick Thomas, Robert Brasseur, Gudrun Aldrian, Frédéric Heitz, Maria A. Muñoz-Morris, Jean-Marie Devoisselle, Gilles Divita, Self-Assembling Peptide-Based Nanoparticles for siRNA Delivery in Primary Cell Lines Small. ,vol. 8, pp. 2184- 2188 ,(2012) , 10.1002/SMLL.201102413