The human cytochrome c oxidase assembly factors SCO1 and SCO2 have regulatory roles in the maintenance of cellular copper homeostasis.

作者: Scot C. Leary , Paul A. Cobine , Brett A. Kaufman , Guy-Hellen Guercin , Andre Mattman

DOI: 10.1016/J.CMET.2006.12.001

关键词:

摘要: … Human SCO1 and SCO2 are metallochaperones that are essential for the assembly of the catalytic core of cytochrome c oxidase (COX). Here we show that they have additional, …

参考文章(37)
Iqbal Hamza, Jonathan D. Gitlin, Copper chaperones for cytochrome c oxidase and human disease. Journal of Bioenergetics and Biomembranes. ,vol. 34, pp. 381- 388 ,(2002) , 10.1023/A:1021254104012
M. J. Petris, J. F. Mercer, J. G. Culvenor, P. Lockhart, P. A. Gleeson, J. Camakaris, Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking. The EMBO Journal. ,vol. 15, pp. 6084- 6095 ,(1996) , 10.1002/J.1460-2075.1996.TB00997.X
Lefkothea C. Papadopoulou, Carolyn M. Sue, Mercy M. Davidson, Kurenai Tanji, Ichizo Nishino, James E. Sadlock, Sindu Krishna, Winsome Walker, Jeanette Selby, D. Moira Glerum, Rudy Van Coster, Gilles Lyon, Emmanuel Scalais, Roger Lebel, Paige Kaplan, Sara Shanske, Darryl C. De Vivo, Eduardo Bonilla, Michio Hirano, Salvatore DiMauro, Eric A. Schon, Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2 , a COX assembly gene Nature Genetics. ,vol. 23, pp. 333- 337 ,(1999) , 10.1038/15513
TD Rae, PJ Schmidt, RA Pufahl, VC Culotta, T V. O'Halloran, Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. Science. ,vol. 284, pp. 805- 808 ,(1999) , 10.1126/SCIENCE.284.5415.805
Paul A. Cobine, Luis D. Ojeda, Kevin M. Rigby, Dennis R. Winge, Yeast contain a non-proteinaceous pool of copper in the mitochondrial matrix. Journal of Biological Chemistry. ,vol. 279, pp. 14447- 14455 ,(2004) , 10.1074/JBC.M312693200
P. Freisinger, R. Horvath, C. Macmillan, J. Peters, M. Jaksch, Reversion of hypertrophic cardiomyopathy in a patient with deficiency of the mitochondrial copper binding protein Sco2: is there a potential effect of copper? Journal of Inherited Metabolic Disease. ,vol. 27, pp. 67- 79 ,(2004) , 10.1023/B:BOLI.0000016614.47380.2F
Ting Y Tao, Jonathan D Gitlin, Hepatic copper metabolism: insights from genetic disease. Hepatology. ,vol. 37, pp. 1241- 1247 ,(2003) , 10.1053/JHEP.2003.50281
Paul A. Cobine, Fabien Pierrel, Megan L. Bestwick, Dennis R. Winge, Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase. Journal of Biological Chemistry. ,vol. 281, pp. 36552- 36559 ,(2006) , 10.1074/JBC.M606839200