Development of a simple pyrene-based ratiometric fluorescent chemosensor for copper ion in living cells

摘要: Abstract A simple pyrene compound ( 1 ) containing thiophene is synthesized and used as ratiometric fluorescent chemosensor to recognize Cu 2+ . The signal change of the on basis monomer–excimer conversion induced by As far we know, it first based that developed for analytical performance characteristics proposed -sensitive are investigated. can be applied quantification with a linear range covering from 1.0 × 10 −7 2.0 × 10 −5  M detection limit 2 × 10 −8  M. experiment results show response behavior toward pH independent under wide 3.0 8.0. Most importantly, changes remarkably specific in presence other metal ions, which meet selective requirements practical application. Moreover, fast (response time less than 2 min). In addition, has been detect water samples image living cells encouraging results.