Radiolabeled nanosystem, process for the preparation thereof and its use

摘要: Disclosed are novel, targeted, self-assembled nanoparticles radiolabeled with technetium-99m (Tc-99m) as radiodiagnostic compositions, methods of using these compositions and for preparing such compositions. Specifically, the composed polyelectrolyte biopolymers having targeting moieties, which can be suitable targeted delivery radionuclide metal ions complexed to nanoparticles. These specifically bind internalize into tumor cells realize receptor mediated uptake. Radiolabeled, nanoparticulate composition, making, radiolabeling in field diagnosis therapy also provided.