Genomic organization of the interleukin-1 locus.
作者： Scott L Taylor , Blair R Renshaw , Kirsten E Garka , Dirk E Smith , John E Sims
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摘要: Recent additions have expanded the interleukin (IL)-1 gene family to 10 members. We determined order, orientation, and intergenic distance of nine IL-1 genes that lie on human chromosome 2. report cDNA sequences for mouse orthologs three these genes. The order orientation been mapped, locus compared with locus. There is a break in > 100 kb, locus, located between Il1b most centromere-proximal novel seems be missing an ortholog IL1F7.
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