Ionic diffusion and space charge polarization in structural characterization of biological tissues.

摘要: In this study, a new approach to the analysis of low-frequency (1-107 Hz) dielectric spectra biological tissue, has been described. The experimental results are interpreted in terms ionic diffusion and space charge polarization according Sawada’s theory. presentation spectra, i.e. ( $\partial \varepsilon ' / \partial \ln f) \cdot f$ used. This method peaks which narrower better resolved than both measured loss an alternative quantity '/ . presented expression have applied changes spatial molecular structure collagen fibril network pericardium tissue exposed glutaraldehyde (GA), with respect native tissue. coefficient ions was estimated on basis dispersion measurement for aqueous NaCl solution well-calibrated distance between electrodes. fitting procedure theoretical function data allowed us determine three diffusive relaxation regions structural parameters $d_{\rm s}$ , describing arrangement fibrils It found that significant decrease from 87 nm 45 may correspond reduction interfibrillar within GA cross-linked