Tannic acid-stabilized pericardium tissue: IR spectroscopy, atomic force microscopy, and dielectric spectroscopy investigations.

摘要: Infrared (IR) spectroscopy, atomic force microscopy (AFM), and dielectric spectroscopy methods were employed to study structural dynamic changes in the tannic acid (TA)-stabilized pericardium tissue. Chemically stabilized tissue is widely used construction of derived bioprostheses. IR spectra recorded range 400–4000 cm−1 allowed us recognize different types TA–collagen interactions. Formation hydrogen bonds between amine as well amide NH groups from collagen hydroxyl TA was analyzed. The AFM imaging showed that stabilization procedure with introduces considerable both surface topography thickness fibrils fibril arrangement on surface. It found, these have an impact behavior TA-stabilized for native tissues measured frequency temperature ranges 10−1 –107 Hz 120–270 K, respectively. revealed relaxation process due orientation bound water supplemented by fluctuation polar side groups. At temperatures above ∼210 ion migration observed. found processes influenced interaction. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res,