BMP Signaling and Stem Cell Self-Renewal in the Drosophila Ovary
作者： Darin Dolezal , Francesca Pignoni
DOI: 10.1016/B978-0-12-405945-0.00005-3
关键词:
摘要: Abstract Bone morphogenetic protein (BMP) ligands from stromal niche cells suppress differentiation and promote germline stem cell self-renewal in the Drosophila ovary. Regulatory factors local extracellular matrix enhance BMP signaling specifically cell. developing surrounding antagonize thereby permitting promoting differentiation. Soma to soma intercellular communication contributes regulation of homeostasis. This complex generates a steep gradient that ensures tight control versus
sci-hub.se 参考文章(110)
R. Wieser, J.L. Wrana, J. Massagué, GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex. The EMBO Journal. ,vol. 14, pp. 2199- 2208 ,(1995) , 10.1002/J.1460-2075.1995.TB07214.X
Deanna S. Smith, Martin Niethammer, Ramses Ayala, Ying Zhou, Michael J. Gambello, Anthony Wynshaw-Boris, Li-Huei Tsai, Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1 Nature Cell Biology. ,vol. 2, pp. 767- 775 ,(2000) , 10.1038/35041000
Andrew Swan, Thuy Nguyen, Beat Suter, Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning Nature Cell Biology. ,vol. 1, pp. 444- 449 ,(1999) , 10.1038/15680
Jeffrey L Wrana, Liliana Attisano, Rotraud Wieser, Francesc Ventura, Joan Massagué, None, Mechanism of activation of the TGF-β receptor Nature. ,vol. 370, pp. 341- 347 ,(1994) , 10.1038/370341A0
Haitao Zhu, Peter Kavsak, Shirin Abdollah, Jeffrey L Wrana, Gerald H Thomsen, None, A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature. ,vol. 400, pp. 687- 693 ,(1999) , 10.1038/23293
Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn, Takuya Nakayama, Jan L. Christian, Rainer Heuchel, Susumu Itoh, Masahiro Kawabata, Nils-Erik Heldin, Carl-Henrik Heldin, Peter ten Dijke, Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling Nature. ,vol. 389, pp. 631- 635 ,(1997) , 10.1038/39369
Nicole E. Faulkner, Denis L. Dujardin, Chin-Yin Tai, Kevin T. Vaughan, Christopher B. O'Connell, Yu-li Wang, Richard B. Vallee, A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function Nature Cell Biology. ,vol. 2, pp. 784- 791 ,(2000) , 10.1038/35041020
Shinji Hirotsune, Mark W. Fleck, Michael J. Gambello, Gregory J. Bix, Amy Chen, Gary D. Clark, David H. Ledbetter, Chris J. McBain, Anthony Wynshaw-Boris, Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality Nature Genetics. ,vol. 19, pp. 333- 339 ,(1998) , 10.1038/1221
Takeshi Imamura, Masao Takase, Ayako Nishihara, Eiichi Oeda, Jun-ichi Hanai, Masahiro Kawabata, Kohei Miyazono, Smad6 inhibits signalling by the TGF-β superfamily Nature. ,vol. 389, pp. 622- 626 ,(1997) , 10.1038/39355
Ting Xie, Allan C Spradling, A Niche Maintaining Germ Line Stem Cells in the Drosophila Ovary Science. ,vol. 290, pp. 328- 330 ,(2000) , 10.1126/SCIENCE.290.5490.328