GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.
作者： R. Wieser , J.L. Wrana , J. Massagué
DOI: 10.1002/J.1460-2075.1995.TB07214.X
关键词:
摘要: … insights into the mechanism of TGF-, receptor activation. The TGF-P type II receptor, TIR-II, is a constitutively active kinase that does not require ligand for activation (Wrana et al., 1994a)…
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