Cryptococcosis in Africa
作者： Nelesh P. Govender , Thomas G. Mitchell , Anastasia P. Litvintseva , Kathleen J. Miglia
DOI: 10.1128/9781555816858.CH20
关键词:
摘要: This chapter reviews the epidemiology, diagnosis, clinical manifestations, treatment, and prognosis of cryptococcosis in Africa ecology population genetics African isolates Cryptococcus. In pre-highly active antiretroviral therapy (HAART) era sub-Saharan Africa, was often a sentinel opportunistic infection among HIV-infected adults, heralding diagnosis AIDS more than 88% cryptococcal cases. The initial meningitis HAART naive, patients is relatively straightforward involves microscopy culture specimens, as well serology. Maintenance with fluconazole usually prescribed for those who survive their episode disease. disease HAART-treated paradoxical immune reconstitution inflammatory syndrome (IRIS) slightly difficult. formidable challenges involve significant problems management, prevention. cases due to C. neoformans far exceed number infections caused by gattii. Sub-Saharan global epicenter HIV/AIDS pandemic. It possible elucidate evolutionary relationships strains Cryptococcus ancestors.
asmscience.org参考文章(142)
R A Lartey, E H Frimpong, Study of the aetiologic agents of meningitis in Kumasi, Ghana, with special reference to Cryptococcal neoformans. East African Medical Journal. ,vol. 75, pp. 516- 519 ,(1998)
K.J. Kwon-Chung, J.E. Bennett, High prevalence of Cryptococcus neoformans var. gattii in tropical and subtropical regions Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale. A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie. ,vol. 257, pp. 213- 218 ,(1984) , 10.1016/S0174-3031(84)80074-8
Kuezina T, Muyembe Tamfum Jj, Mupapa Kibadi D, Vandepitte J, Ngwala-Bikindu D, Kela-We I, Nganda L, [Cryptococcosis caused by Cryptococcus neoformans var. Gattii. A case associated with acquired immunodeficiency syndrome (AIDS) in Kinshasa, Zaire]. Médecine tropicale : revue du Corps de santé colonial. ,vol. 52, pp. 435- 438 ,(1992)
J Mboussa, A M Kissila, G Mouanga-Yidika, B Carme, A Itoua-Ngaporo, G M Aya, A Mbitsi, P M'Pele, Opportunistic parasitic diseases and mycoses in AIDS. Their frequencies in Brazzaville (Congo) Bulletin De La Societe De Pathologie Exotique. ,vol. 81, pp. 311- 316 ,(1988)
Thomas G. Mitchell, Anastasia P. Litvintseva, Typing Species of Cryptococcus and Epidemiology of Cryptococcosis Springer, Berlin, Heidelberg. pp. 167- 190 ,(2010) , 10.1007/978-3-642-03150-2_8
Nyadedzor C, Taneguchi K, Cofie Cn, Newman M, Sata T, Tsiagbe Vk, Ayisi Nk, Wiredu Ek, T-lymphocytopaenia, opportunistic infections and pathological findings in Ghanaian AIDS patients and their sexual partners East African Medical Journal. ,vol. 74, pp. 784- 791 ,(1997)
Elias Ml, El-Kebbi Ra, Karam El-Din Az, Soliman Ak, Wasfy Mm, Mahoney Fj, Ismail Tf, Earhart Kc, Pimentel G, Sultan Ya, Mansour Am, Isolation of cryptococcus, Candida, Aspergillus, Rhodotorula and nocardia from meningitis patients in egypt. The Journal of the Egyptian Public Health Association. ,vol. 84, pp. 169- ,(2009)
Ki-Zerbo Ga, Yaméogo I, Sawadogo A, Lankoandé D, Andonaba Jb, Sawadogo Ab, Millogo A, [Cryptococcal meningitis in HIV-infected patients at Bobo-Dioulasso hospital (Burkina Faso)]. Bulletin De La Societe De Pathologie Exotique. ,vol. 97, pp. 119- 121 ,(2004)
M Takashio, R Vanbreuseghem, An atypical strain of Cryptococcus neoformans (San Felice) Vuillemin 1894. II. Cryptococcus neoformans var. gattii var. nov. Annales de la Societe belge de medecine tropicale. ,vol. 50, pp. 695- 702 ,(1970)
Xu JianPing, D. H. Howard, T. G. Mitchell, Population genetic analyses of medically important fungi. Marcel Dekker, Inc.. pp. 703- 722 ,(2002)