CDK inhibitors for muscle stem cell differentiation and self-renewal.
作者： Amrudha Mohan , Atsushi Asakura
DOI: 10.7600/JPFSM.6.65
关键词:
摘要: Regeneration of muscle is undertaken by stem cell populations named satellite cells which are normally quiescent or at the G0 phase cycle. However, upon signals from damaged muscle, lose their quiescence, and enter G1 cycle to expand population progenies termed myogenic precursor (MPCs). Eventually, MPCs stop undergo terminal differentiation form skeletal fibers. Some retract as a self-renewal process. Therefore, regulation, consisting activation, proliferation, self-renewal, key event regeneration. In this review, we summarize up-to-date progress on research about regulation progenitor during embryonic myogenesis adult regeneration, aging, exercise diseases including muscular dystrophy fiber atrophy, especially focusing cyclin-dependent kinase inhibitors (CDKIs).
ceek.jp参考文章(124)
Lisa A Porter, Daniel J Donoghue, Cyclin B1 and CDK1: Nuclear Localization and Upstream Regulators Progress in cell cycle research. ,vol. 5, pp. 335- 347 ,(2003)
L. Wells, K. A. Edwards, S. I. Bernstein, Myosin heavy chain isoforms regulate muscle function but not myofibril assembly. The EMBO Journal. ,vol. 15, pp. 4454- 4459 ,(1996) , 10.1002/J.1460-2075.1996.TB00822.X
Nobuaki Chinzei, Shinya Hayashi, Takeshi Ueha, Takaaki Fujishiro, Noriyuki Kanzaki, Shingo Hashimoto, Shuhei Sakata, Shinsuke Kihara, Masahiko Haneda, Yoshitada Sakai, Ryosuke Kuroda, Masahiro Kurosaka, P21 Deficiency Delays Regeneration of Skeletal Muscular Tissue PLOS ONE. ,vol. 10, ,(2015) , 10.1371/JOURNAL.PONE.0125765
Antonio Di Cristofano, Marika De Acetis, Andrew Koff, Carlos Cordon-Cardo, Pier P Pandolfi, Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse. Nature Genetics. ,vol. 27, pp. 222- 224 ,(2001) , 10.1038/84879
Véronique Gire, Vjekoslav Dulić, Senescence from G2 arrest, revisited Cell Cycle. ,vol. 14, pp. 297- 304 ,(2015) , 10.1080/15384101.2014.1000134
Matthew L. Fero, Erin Randel, Kay E. Gurley, James M. Roberts, Christopher J. Kemp, The murine gene p27Kip1 is haplo-insufficient for tumour suppression Nature. ,vol. 396, pp. 177- 180 ,(1998) , 10.1038/24179
M. Pagano, R. Pepperkok, F. Verde, W. Ansorge, G. Draetta, Cyclin A is required at two points in the human cell cycle. The EMBO Journal. ,vol. 11, pp. 961- 971 ,(1992) , 10.1002/J.1460-2075.1992.TB05135.X
Tao Cheng, Neil Rodrigues, David Dombkowski, Sebastian Stier, David T. Scadden, Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nature Medicine. ,vol. 6, pp. 1235- 1240 ,(2000) , 10.1038/81335
XIAO-XIANG Zhu, K Kozarsky, JR Strahler, C Eckerskorn, F Lottspeich, R Melhem, J Lowe, DA Fox, SM Hanash, GF Atweh, None, Molecular cloning of a novel human leukemia-associated gene. Evidence of conservation in animal species. Journal of Biological Chemistry. ,vol. 264, pp. 14556- 14560 ,(1989) , 10.1016/S0021-9258(18)71714-6
David Sidransky, Geoffrey I. Shapiro, Christian D. Edwards, Li Mao, Barrett J. Rollins, Gauri Bedi, Adrian Merlo, A Novel p16INK4A Transcript Cancer Research. ,vol. 55, pp. 2995- 2997 ,(1995)