Attenuation of Weight Gain and Prevention of Associated Pathologies by Inhibiting SSAO

摘要: Obesity is a worldwide prevalent metabolic disorder that associated with diabetes, among many other diseases. Bearing this in mind, prevention and treatment ways need to be improved. Notably, activity of the enzyme semicarbazide-sensitive amine oxidase (SSAO) found elevated overweight subjects. Moreover, SSAO inhibition has resulted an increase histamine adipose tissue limitation body fat. The current review aims overview risks obesity, rationalize molecular activity, outline strategies inhibiting upregulated levels. It describes differences between inhibitors advances prospective agents. Based on evidence, caffeine proposed as effective, safe, reliable choice inhibit activity. Furthermore, adipocytes been Therefore, it suggested one key compounds studied for obesity management. To conclude, may attenuate weight gain prevent related