Pro-gastrin-releasing peptide (Pro-GRP), a tumor marker for small cell lung cancer.

摘要: Introduction: Gastrin-releasing peptide (Pro-GRP), a member of the bombesin family peptides, has been shown to have mitogenic activity in small cell lung carcinoma (SCLC), and be produced by SCLC an autocrine fashion. We investigated usefulness serum pro-gastrin-releasing (Pro-GRP) as tumor marker for diagnosis, treatment monitoring patients with cancer (SCLC). Materials Methods: This study comprised 80 healthy individuals. Serum samples were also obtained from carcinoma, 20 chronic bronchitis, 30 sarcoidosis fibrosis. The cut-off level Pro-GRP was set at 34.2 pg/ml. Results: levels benign diseases significantly higher than those group. elevated patients. elevation that reference Conclusion: These results show may potential carcinoma.