Long open tubular molecule imprinted polymer capillary columns with excellent separation efficiencies in chiral and non-chiral separation by capillary electrochromatography.

作者: Shabi Abbas Zaidi , Won Jo Cheong

DOI: 10.1002/ELPS.200800541

关键词:

摘要: Long open tubular S-ketoprofen molecule imprinted polymer capillary columns (1, 2, and 3 m) with the number of theoretical plates (N) over a million for both chrial non-chiral CEC separation have been prepared. Chiral racemic ketoprofen other profen drugs achieved excellent efficiency good selectivity after optimization chromatographic conditions. The N value per column was not proportional to effective length although it increased length. This study has shown outstanding prospect strategy form porous rugged layer in moderately long (1 polymer-CEC studies.

参考文章(30)
Gerald Gübitz, Martin G. Schmid, Chiral separations : methods and protocols Humana. ,(2004)
Stellan Hjertén, High-performance electrophoresis : Elimination of electroendosmosis and solute adsorption Journal of Chromatography A. ,vol. 347, pp. 191- 198 ,(1985) , 10.1016/S0021-9673(01)95485-8
Roberto Mandrioli, Maria A. Raggi, Advances in the enantioseparation of second-generation antidepressant drugs by electrodriven methods Electrophoresis. ,vol. 27, pp. 213- 221 ,(2006) , 10.1002/ELPS.200500297
Dorothee Wistuba, Volker Schurig, Comparison of monolithic approaches for enantioselective capillary electrochromatography involving cyclodextrins. Journal of Separation Science. ,vol. 29, pp. 1344- 1352 ,(2006) , 10.1002/JSSC.200600114
Yoshihide Tanaka, Shigeru Terabe, Recent advances in enantiomer separations by affinity capillary electrophoresis using proteins and peptides. Journal of Biochemical and Biophysical Methods. ,vol. 48, pp. 103- 116 ,(2001) , 10.1016/S0165-022X(01)00143-9
Quanzhou Luo, Guihua Yue, Gary A. Valaskovic, Ye Gu, Shiaw-Lin Wu, Barry L. Karger, On-Line 1D and 2D Porous Layer Open Tubular/LC-ESI-MS Using 10-μm-i.d. Poly(styrene−divinylbenzene) Columns for Ultrasensitive Proteomic Analysis Analytical Chemistry. ,vol. 79, pp. 6174- 6181 ,(2007) , 10.1021/AC070583W
Oscar Salas-Solano, Emanuel Carrilho, Lev Kotler, Arthur W. Miller, Wolfgang Goetzinger, Zoran Sosic, Barry L. Karger, Routine DNA sequencing of 1000 bases in less than one hour by capillary electrophoresis with replaceable linear polyacrylamide solutions. Analytical Chemistry. ,vol. 70, pp. 3996- 4003 ,(1998) , 10.1021/AC980457F
Liguo Song, Dehai Liang, Zijian Chen, Dufei Fang, Benjamin Chu, DNA sequencing by capillary electrophoresis using mixtures of polyacrylamide and poly(N,N-dimethylacrylamide) Journal of Chromatography A. ,vol. 915, pp. 231- 239 ,(2001) , 10.1016/S0021-9673(01)00593-3
Jayna J. Shah, Jon Geist, Laurie E. Locascio, Michael Gaitan, Mulpuri V. Rao, Wyatt N. Vreeland, Surface modification of poly(methyl methacrylate) for improved adsorption of wall coating polymers for microchip electrophoresis. Electrophoresis. ,vol. 27, pp. 3788- 3796 ,(2006) , 10.1002/ELPS.200600118
Chuen-Ying Liu, Chun-Chi Lin, An insight into molecularly imprinted polymers for capillary electrochromatography Electrophoresis. ,vol. 25, pp. 3997- 4007 ,(2004) , 10.1002/ELPS.200406160