Temperature Dependence of Transcytotic Pathways in Rat Liver
作者： H. Klapper , J. Graf , R. Fuchs
DOI: 10.1007/978-3-642-84295-5_37
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摘要: The liver is a transporting epithelium, composed of sheets hepatocytes that separate the canalicular lumen from perisinusoidal space. Transport macromolecules blood to bile thought occur by transcellular vesicular pathway (Brown and Kloppel, 1989; Lake et al. 1985), where internalize extracellular material either specific receptors or fluidphase endocytosis. Ligands taken up receptor-mediated endocytosis are selectively delivered lysosomes (e.g. asialoglycoproteins) transcytosis polymeric immunoglobulin A). Transcellular transport majority other derived biliary proteins (Reuben, 1984) does not involve receptor binding.
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