Mild cognitive impairment: an update in Parkinson's disease and lessons learned from Alzheimer's disease
作者： Jennifer G Goldman , Neelum T Aggarwal , Cynthia D Schroeder
DOI: 10.2217/NMT.15.34
关键词:
摘要: Cognitive dysfunction is an important focus of research in Parkinson's disease (PD) and Alzheimer's (AD). While the concept amnestic mild cognitive impairment (MCI) as a prodrome to AD has been recognized for many years, construct MCI PD relative newcomer with recent development diagnostic criteria, biomarker programs treatment trials. Controversies challenges, however, regarding PD-MCI's definition, application, heterogeneity different trajectories have arisen. This review will highlight current advances challenges PD-MCI. Furthermore, lessons from field, which witnessed evolution MCI/AD definitions, relevant disease-modifying targeted therapeutic trials be discussed.
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