The Common Mutations C677T and A1298C in the Human Methylenetetrahydrofolate Reductase Gene Are Associated with Hyperhomocysteinemia and Cardiovascular Disease in Hemodialysis Patients
作者： Y.S. Haviv , V. Shpichinetsky , N. Goldschmidt , I. Abou Atta , A. Ben-Yehuda
DOI: 10.1159/000064485
关键词:
摘要: Background: Plasma total homocysteine (tHcy) level might be an important risk factor for the development of cardiovascular disease (CVD) in dialysis patients. While both renal failu
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B G Han, D S Yoon, Y H Shim, H J Lee, E Y Lee, J S Kim, S O Choi, Do dialysis patients need extra folate supplementation Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. ,vol. 15, pp. 247- 250 ,(1999)
Simonsen O, Andersson A, Hultberg B, Thysell H, Nilsson-Ehle P, Arnadottir M, Brattström L, The effect of high-dose pyridoxine and folic acid supplementation on serum lipid and plasma homocysteine concentrations in dialysis patients. Clinical Nephrology. ,vol. 40, pp. 236- 240 ,(1993)
C. Novembrino, P. Colucci, S. Finazzi, A. T. Maiolo, F. Bamonti-Catena, A. F. De Vecchi, E. Taioli, G. Lando, M. De Franceschi, C. Patrosso, A. Marocchi, Homocysteine, vitamin B12, serum and erythrocyte folate in peritoneal dialysis patients. Clinical Nephrology. ,vol. 55, pp. 313- 317 ,(2001)
Godfried H. J. Boers, Frans J. M. Trijbels, Diana G. Franken, Erik M. B. Stevens, Henk J. Blom, Astrid M. T. Engbersen, Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia American Journal of Human Genetics. ,vol. 56, pp. 142- 150 ,(1995)
Gideon Friedman, Netta Goldschmidt, Yechiel Friedlander, Arie Ben-Yehuda, Jacob Selhub, Sharona Babaey, Malka Mendel, Miriam Kidron, Hanoch Bar-On, A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations. Journal of Nutrition. ,vol. 129, pp. 1656- 1661 ,(1999) , 10.1093/JN/129.9.1656
Vlad Shpichinetsky, Itamar Raz, Yechiel Friedlander, Neta Goldschmidt, Isaiah D. Wexler, Arie Ben-Yehuda, Gideon Friedman, The Association between Two Common Mutations C677T and A1298C in Human Methylenetetrahydrofolate Reductase Gene and the Risk for Diabetic Nephropathy in Type II Diabetic Patients Journal of Nutrition. ,vol. 130, pp. 2493- 2497 ,(2000) , 10.1093/JN/130.10.2493
M T Shipchandler, E G Moore, Rapid, fully automated measurement of plasma homocyst(e)ine with the Abbott IMx analyzer. Clinical Chemistry. ,vol. 41, pp. 991- 994 ,(1995) , 10.1093/CLINCHEM/41.7.991
Andrew G. Bostom, Douglas Shemin, Petra Verhoef, Marie R. Nadeau, Paul F. Jacques, Jacob Selhub, Lance Dworkin, Irwin H. Rosenberg, Elevated Fasting Total Plasma Homocysteine Levels and Cardiovascular Disease Outcomes in Maintenance Dialysis Patients A Prospective Study Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 17, pp. 2554- 2558 ,(1997) , 10.1161/01.ATV.17.11.2554
Richard Tremblay, Alain Bonnardeaux, David Geadah, Lambert Busque, Michel Lebrun, Denis Ouimet, Martine Leblanc, Hyperhomocysteinemia in hemodialysis patients: Effects of 12-month supplementation with hydrosoluble vitamins Kidney International. ,vol. 58, pp. 851- 858 ,(2000) , 10.1046/J.1523-1755.2000.00234.X
Manuela Födinger, Christine Mannhalter, Gabriele Wölfl, Ingrid Pabinger, Eva Müller, Rainer Schmid, Walter H. Hörl, Gere Sunder-Plassmann, Mutation (677 C to T) in the methylenetetrahydrofolate reductase gene aggravates hyperhomocysteinemia in hemodialysis patients Kidney International. ,vol. 52, pp. 517- 523 ,(1997) , 10.1038/KI.1997.362