Selective monoalkylation of p-tert-butylcalix-[4]-arene in a methyl carbonate ionic liquid.
作者： R. E. Whiteside , H. Q. Nimal Gunaratne , A. F. V. Muzio , P. Nockemann
DOI: 10.1039/C8CC05566A
关键词:
摘要: Methyl carbonate ionic liquids are shown to readily mono-deprotonate p-tert-butylcalix-[4]-arenes initiating the formation of an organic mono-anionic p-tert-butylcalix-[4]-arate salt, methanol and carbon dioxide. These calix-[4]-arate salts have been successfully used in alkylation reactions with dialkyl sulfates alkyl halides form a mono-alkylated single product high yield. This method avoids common use alkali metal bases such as caesium fluoride hence providing safer more selective synthetic route.
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