Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways.

作者: Hongmei Yu , Qi Li , Victor P. Kolosov , Juliy M. Perelman , Xiangdong Zhou

DOI: 10.1002/JAT.1679

关键词:

摘要: … Hypoxia inducible factor-1 (HIF-1) is a transcriptional factor which can be stimulated to bind … of COPD. We hypothesize that cigarette smoke up-regulates HIF-1α production and HIF-1 …

参考文章(52)
Rémi Mounier, Bente Klarlund Pedersen, Peter Plomgaard, Muscle‐specific expression of hypoxia‐inducible factor in human skeletal muscle Experimental Physiology. ,vol. 95, pp. 899- 907 ,(2010) , 10.1113/EXPPHYSIOL.2010.052928
Timothy S. Lewis, Paul S. Shapiro, Natalie G. Ahn, Signal Transduction through MAP Kinase Cascades Advances in Cancer Research. ,vol. 74, pp. 49- 139 ,(1998) , 10.1016/S0065-230X(08)60765-4
B. H. Jiang, G. L. Semenza, C. Bauer, H. H. Marti, Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. American Journal of Physiology-cell Physiology. ,vol. 271, ,(1996) , 10.1152/AJPCELL.1996.271.4.C1172
Linsey E. Haswell, Katherine Hewitt, David Thorne, Audrey Richter, Marianna D. Gaça, Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: A potential model of goblet cell hyperplasia Toxicology in Vitro. ,vol. 24, pp. 981- 987 ,(2010) , 10.1016/J.TIV.2009.12.019
Thomas Hellwig-Bürgel, Daniel P. Stiehl, Anika E. Wagner, Eric Metzen, Wolfgang Jelkmann, Review: Hypoxia-Inducible Factor-1 (HIF-1): A Novel Transcription Factor in Immune Reactions Journal of Interferon and Cytokine Research. ,vol. 25, pp. 297- 310 ,(2005) , 10.1089/JIR.2005.25.297
Abdelhamid Almolki, Armelle Guenegou, Slawomir Golda, Laurent Boyer, Mourad Benallaoua, Nadia Amara, Rafik Bachoual, Clémence Martin, François Rannou, Sophie Lanone, Jozef Dulak, Pierre-Régis Burgel, Jamel El-Benna, A. Benedicte Leynaert, Michel Aubier, Jorge Boczkowski, Heme Oxygenase-1 Prevents Airway Mucus Hypersecretion Induced by Cigarette Smoke in Rodents and Humans The American Journal of Pathology. ,vol. 173, pp. 981- 992 ,(2008) , 10.2353/AJPATH.2008.070863
William G. Kaelin, Peter J. Ratcliffe, Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway Molecular Cell. ,vol. 30, pp. 393- 402 ,(2008) , 10.1016/J.MOLCEL.2008.04.009
Mary Callaghan Rose, Judith A. Voynow, Respiratory Tract Mucin Genes and Mucin Glycoproteins in Health and Disease Physiological Reviews. ,vol. 86, pp. 245- 278 ,(2006) , 10.1152/PHYSREV.00010.2005
Qunzhou Zhang, Zuo-Feng Zhang, Jian Y. Rao, J. Denry Sato, Jimmy Brown, Diana V. Messadi, Anh D. Le, Treatment with siRNA and antisense oligonucleotides targeted to HIF-1α induced apoptosis in human tongue squamous cell carcinomas International Journal of Cancer. ,vol. 111, pp. 849- 857 ,(2004) , 10.1002/IJC.20334
L Xu, M B Nilsson, P Saintigny, T Cascone, M H Herynk, Z Du, P G Nikolinakos, Y Yang, L Prudkin, D Liu, J J Lee, F M Johnson, K-K Wong, L Girard, A F Gazdar, J D Minna, J M Kurie, I I Wistuba, J V Heymach, Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1α in non-small cell lung cancer cells Oncogene. ,vol. 29, pp. 2616- 2627 ,(2010) , 10.1038/ONC.2010.16