Diagnosis and Prognosis of Male Infertility in Mammal: The Focusing of Tyrosine Phosphorylation and Phosphotyrosine Proteins

摘要: Male infertility refers to the inability of a man achieve pregnancy in fertile female. In more than one-third cases, arises due male factor. Therefore, developing strategies for diagnosis and prognosis is critical. Simultaneously, satisfactory model cellular mechanisms that regulate normal sperm function must be established. this regard, tyrosine phosphorylation one most common through which several signal transduction pathways are adjusted spermatozoa. It regulates various aspects function, example, motility, hyperactivation, capacitation, acrosome reaction, fertilization, beyond. Several recent large-scale studies have identified proteins phosphorylated spermatozoa acquire fertilization competence. However, these basal not presented an overall mechanism infertility. review, we focus...