Gastrointestinal Aspergillosis and Zygomycosis of Cattle

摘要: Gastrointestinal mycosis was diagnosed in 73 lesions of 32 cattle without a history ofengorgement, and tissues 29 animals were examined histopathologically. The omasum the target organ for infection, followed by rumen reticulum. Acute necrohemorrhagic dominated, with infiltration neutrophils thrombosis. etiologic diagnosis accomplished indirect immunohistochemical staining fungal elements panel mono- polyclonal antibodies raised against antigens. Aspergillosis zygomycosis one or more organs 11 (34.4%) 20 (62.5%) cattle, respectively, dual infections found three two animals. Candidosis only case. Hematogenous spread fungi predominantly to liver seen nine Lymphogenic aspergilli mesenteric omasal lymph nodes occurred animals, respectively. Factors that seemed predispose mycotic infection included presence other diseases intense antimicrobial therapy. These factors post-partum status, which 23 (79.3%) cows, predisposed several ways, e.g., reflux acidic abomasal contents into forestomachs, stasis proventricular content, metabolic dys- functions, stress. Bovine aspergillosis, candidosis, are worldwide. is caused genus Aspergillus, candidosis Candida, class Zygo- mycetes. In Denmark most countries, infec- tions Aspergillus fumi- gatus, Candida albicans, Absidia ~oryrnbifera.~-~ .~~- 16,22,24-26.31.34 Also Rhizomucor (Mucor) pusillus Rhizopus spp. may play an role bovine zygomyc~sis.~~~~ ~~~~~~~~~ widespread external internal environment cattle,".'" predisposing seem be required before tion establi~hed.~~~~ ~~~'~~~~.~~~~' main portals en- try respiratory gastrointestinal tracts. Pri- mary pulmonary mainly established subsequent exposure heavy loads spores from moldy food stuffs. pathogenesis obscure but seems complex, number conditions have been incriminated as im- portant acidosis following engorgement grains.25.34 young grass,I" intensive sequela sepsis contents,31 feeding stuff~,'~.~~ disturbances stress peri~d.~.'.~~ Viral erosive diseases, such infectious rhinotracheitis mucosal disease, thought because mechanical damage mucous membranes