The effect of a high progesterone concentration before oocyte retrieval on the peri-implantation endometrium

作者: Liu Liu , Sumaia Sailan , Tinchiu Li , Najat Mariee , Susan Laird

DOI: 10.1016/J.RBMO.2015.09.003

关键词:

摘要: In this single-centre, prospective cohort study, the effect of high progesterone level before oocyte retrieval on endometrial morphology and uterine natural killer cell (uKN) count in peri-implantation period was investigated. A total 106 women undergoing IVF treatment who did not proceed to fresh embryo transfer were included. Endometrial samples obtained 7 days after HCG administration. Multiple regression analysis used identify factors affecting results histological staging uNK count. Progesterone day administration only significant variable associated with (P = 0.004). development significantly < 0.001) more advanced than that normal progesterone; The median (range) 9.6% (2.3-21.6%) higher 5.7% (1.4-18.7%) progesterone. High correlated advancement as well increased

参考文章(49)
Hai-yan Zhu, Xiao-ying Jin, Xiao-mei Tong, Liu Liu, Feng Zhou, Song-ying Zhang, Xiao-na Lin, Chao Li, A frozen-thawed embryo transfer program improves the embryo utilization rate. Chinese Medical Journal. ,vol. 122, pp. 1974- 1978 ,(2009)
R.W. Noyes, A.T. Hertig, J. Rock, Dating the endometrial biopsy. Fertility and Sterility. ,vol. 1, pp. 3- 25 ,(1950) , 10.1016/S0015-0282(16)30062-0
Judith N. Bulmer, Lynn Morrison, Margaret Longfellow, Anne Ritson, Denise Pace, Granulated lymphocytes in human endometrium: histochemical and immunohistochemical studies Human Reproduction. ,vol. 6, pp. 791- 798 ,(1991) , 10.1093/OXFORDJOURNALS.HUMREP.A137430
Liu Liu, Lijuan Zhao, Tin Chiu Li, Haiyan Zhu, Xiaona Lin, Xiaoying Jin, Xiaomei Tong, Songying Zhang, Comparison of progesterone measurement on day of, and day after, HCG administration in IVF–embryo transfer cycles Reproductive Biomedicine Online. ,vol. 30, pp. 157- 165 ,(2015) , 10.1016/J.RBMO.2014.10.017
L. Aghajanova, A.E. Hamilton, L.C. Giudice, Uterine Receptivity to Human Embryonic Implantation: Histology, Biomarkers, and Transcriptomics Seminars in Cell & Developmental Biology. ,vol. 19, pp. 204- 211 ,(2008) , 10.1016/J.SEMCDB.2007.10.008
Wei Guo, Pengfei Li, Guangfeng Zhao, Hongye Fan, Yali Hu, Yayi Hou, Glucocorticoid Receptor Mediates the Effect of Progesterone on Uterine Natural Killer Cells American Journal of Reproductive Immunology. ,vol. 67, pp. 463- 473 ,(2012) , 10.1111/J.1600-0897.2012.01114.X
Osman H Develioglu, Jeng-Gwang Hsiu, George Nikas, James P Toner, Sergio Oehninger, Howard W Jones, Endometrial estrogen and progesterone receptor and pinopode expression in stimulated cycles of oocyte donors. Fertility and Sterility. ,vol. 71, pp. 1040- 1047 ,(1999) , 10.1016/S0015-0282(99)00137-5
Shalini C. Lobo, S.-T. Joseph Huang, Ariane Germeyer, Chrysoula Dosiou, Kim Chi Vo, Suzana Tulac, Nihar R. Nayak, Linda C. Giudice, The Immune Environment in Human Endometrium during the Window of Implantation American Journal of Reproductive Immunology. ,vol. 52, pp. 244- 251 ,(2004) , 10.1111/J.1600-0897.2004.00217.X
Liu Liu, Feng Zhou, Xiaona Lin, Tinchiu Li, Xiaomei Tong, Haiyan Zhu, Songying Zhang, Recurrent IVF failure is associated with elevated progesterone on the day of hCG administration European Journal of Obstetrics & Gynecology and Reproductive Biology. ,vol. 171, pp. 78- 83 ,(2013) , 10.1016/J.EJOGRB.2013.08.025
Ze Wu, Rong Li, Yanping Ma, Bo Deng, Xiaomei Zhang, Yushi Meng, Xinna Chen, Ping Liu, Jie Qiao, Effect of HCG-day serum progesterone and oestradiol concentrations on pregnancy outcomes in GnRH agonist cycles Reproductive Biomedicine Online. ,vol. 24, pp. 511- 520 ,(2012) , 10.1016/J.RBMO.2012.02.003