Telomere-Targeted Retrotransposons in the Rice Blast Fungus Magnaporthe oryzae: Agents of Telomere Instability

作者: John H. Starnes , David W. Thornbury , Olga S. Novikova , Cathryn J. Rehmeyer , Mark L. Farman

DOI: 10.1534/GENETICS.111.137950

关键词:

摘要: The fungus Magnaporthe oryzae is a serious pathogen of rice and other grasses. Telomeric restriction fragments in isolates that infect perennial ryegrass (prg) are hotspots for genomic rearrangement undergo frequent, spontaneous alterations during fungal culture. telomeres rice-infecting very stable by comparison. Sequencing chromosome ends from number prg-infecting revealed two related non-LTR retrotransposons (M. Retrotransposons or MoTeRs) inserted the telomere repeats. This contrasts with uninterrupted sequences. Genetic evidence indicates MoTeR elements responsible observed instability. MoTeRs represent new family telomere-targeted transposons whose members found exclusively fungi.

参考文章(82)
Barbara Perrini, Lucia Piacentini, Laura Fanti, Fabio Altieri, Silvia Chichiarelli, Maria Berloco, Carlo Turano, Anna Ferraro, Sergio Pimpinelli, HP1 Controls Telomere Capping, Telomere Elongation, and Telomere Silencing by Two Different Mechanisms in Drosophila Molecular Cell. ,vol. 15, pp. 467- 476 ,(2004) , 10.1016/J.MOLCEL.2004.06.036
Serap Aksoy, Suzanne Williams, Sandy Chang, Frank F. Richards, SLACS retrotransposon from Trypanosoma brucei gambiense is similar to mammalian LINEs. Nucleic Acids Research. ,vol. 18, pp. 785- 792 ,(1990) , 10.1093/NAR/18.4.785
Isabelle Fudal, Heidi U. Böhnert, Didier Tharreau, Marc-Henri Lebrun, Transposition of MINE, a composite retrotransposon, in the avirulence gene ACE1 of the rice blast fungus Magnaporthe grisea. Fungal Genetics and Biology. ,vol. 42, pp. 761- 772 ,(2005) , 10.1016/J.FGB.2005.05.001
Fiona E Pryde, Hazel C Gorham, Edward J Louis, Chromosome ends: all the same under their caps. Current Opinion in Genetics & Development. ,vol. 7, pp. 822- 828 ,(1997) , 10.1016/S0959-437X(97)80046-9
Haruhiko Fujiwara, Mizuko Osanai, Takumi Matsumoto, Kenji K. Kojima, Telomere-specific non-LTR retrotransposons and telomere maintenance in the silkworm, Bombyx mori Chromosome Research. ,vol. 13, pp. 455- 467 ,(2005) , 10.1007/S10577-005-0990-9
Dongmei D. Luan, Malka H. Korman, John L. Jakubczak, Thomas H. Eickbush, Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition Cell. ,vol. 72, pp. 595- 605 ,(1993) , 10.1016/0092-8674(93)90078-5