Targeting Apoptosis via Chemical Design: Inhibition of Bid-Induced Cell Death by Small Organic Molecules
作者： Barbara Becattini , Sina Sareth , Dayong Zhai , Kevin J. Crowell , Marilisa Leone
DOI: 10.1016/J.CHEMBIOL.2004.05.022
关键词:
摘要: … basis for its function have not yet been characterized. The three-dimensional structure of … By screening of a small library of compounds using NMR, we isolated pairs of molecules that …
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sci-hub.se 参考文章(52)
Dawei Li, Eugene F. DeRose, Robert E. London, The inter-ligand Overhauser effect: a powerful new NMR approach for mapping structural relationships of macromolecular ligands. Journal of Biomolecular NMR. ,vol. 15, pp. 71- 76 ,(1999) , 10.1023/A:1008360208627
Oliver Zerbe, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, BioNMR in drug research Wiley-VCH. ,(2003)
Shie-Pon Tzung, Kristine M. Kim, Gorka Basañez, Chris D. Giedt, Julian Simon, Joshua Zimmerberg, Kam Y. J. Zhang, David M. Hockenbery, Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nature Cell Biology. ,vol. 3, pp. 183- 191 ,(2001) , 10.1038/35055095
M. Degli Esposti, The roles of Bid. Apoptosis. ,vol. 7, pp. 433- 440 ,(2002) , 10.1023/A:1020035124855
P. J. Hajduk, DRUG DESIGN: Discovering High-Affinity Ligands for Proteins Science. ,vol. 278, pp. 497- 499 ,(1997) , 10.1126/SCIENCE.278.5337.497
Xiao-Ming Yin, Kun Wang, Atan Gross, Yongge Zhao, Sandra Zinkel, Barbara Klocke, Kevin A. Roth, Stanley J. Korsmeyer, Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis Nature. ,vol. 400, pp. 886- 891 ,(1999) , 10.1038/23730
Sina Sareth, Shinichi Kitada, Maurizio Pellecchia, Dayong Zhai, John C Reed, Marilisa Leone, Cancer Prevention by Tea Polyphenols Is Linked to Their Direct Inhibition of Antiapoptotic Bcl-2-Family Proteins Cancer Research. ,vol. 63, pp. 8118- 8121 ,(2003)
Nickolay Brustovetsky, Janet M. Dubinsky, Bruno Antonsson, Ronald Jemmerson, Two pathways for tBID-induced cytochrome c release from rat brain mitochondria: BAK- versus BAX-dependence. Journal of Neurochemistry. ,vol. 84, pp. 196- 207 ,(2002) , 10.1046/J.1471-4159.2003.01545.X
Atan Gross, Vamsi K. Mootha, Tullia Lindsten, Mona Ashiya, Craig B. Thompson, Michael C. Wei, Stanley J. Korsmeyer, Solly Weiler, tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c Genes & Development. ,vol. 14, pp. 2060- 2071 ,(2000) , 10.1101/GAD.14.16.2060
J. M. Adams, The Bcl-2 Protein Family: Arbiters of Cell Survival Science. ,vol. 281, pp. 1322- 1326 ,(1998) , 10.1126/SCIENCE.281.5381.1322