Effects of Mirazid® and myrrh volatile oil on adult Fasciola gigantica under laboratory conditions

作者: AM Massoud , HA Shalaby , RM El Khateeb , MS Mahmoud , MA Kutkat

DOI: 10.1016/S2221-1691(12)60246-9

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摘要: Abstract Objective To evaluate the effects of Mirazid® and myrrh volatile oil on adult Fasciola gigantica ( F. ) under laboratory conditions. Methods The oleoresin extract (Mirazid®) surface morphology following treatment in vitro had been determined by scanning electron microscopy. results were compared with those observed fluke tegument incubation triclabendazole sulphoxide (TCBZ-SO), active form, (Fasinex®, Ciba-Geigy). Results Observations efficacy indicated that both products showed dose-dependent anthelmintic efficacy. anterior half was consistently more severely affected than posterior half. changes induced less severe after exposure to either or TCBZ-SO. Flukes swelling these treatments, but its level blebbing much greater oil; which patches tegumental sloughing apical cone mid-body region flukes. This not extract. Conclusions comparatively disruption, exposed specimens, might suggest activity oleo resin attributed content oil. So, increasing concentration possibly help developing activity.

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