Effect of vitamin A deficiency on guinea pig Peyer's patches

摘要: Abstract The effect of vitamin A deficiency on guinea pig Peyer's patches (PP) was studied. Three groups young pigs were maintained for a period six weeks, each group either A-free diet, or the same diet containing A, vitamin-supplemented by pair feeding. Weight gain A-deficient animals ceased in 5th week. On day sacrifice animals, serum concentration and fed (PF) respectively 3.0±0.9 69.0±4.0 μg/100 ml. Hemoglobin total protein appeared slightly reduced compared to PF control animals. Number ilea those significantly reduced. Rosette-forming immunoglobulin-bearing cells their gut-associated lymphoid tissues (GALT) also significantly. results suggest that leads impaired distribution PP lymphocytes, as result which role GALT local immunity may be hampered.