Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma

作者: Rebecca Favaro , Irene Appolloni , Serena Pellegatta , Alexandra Badiola Sanga , Pierfrancesco Pagella

DOI: 10.1158/0008-5472.CAN-13-1942

关键词:

摘要: These findings define an immunotherapeutic target for treatment of a form brain malignancy, which acts by depleting cancer stem-like cells required to sustain the malignancy in mouse model system.

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