Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.
作者： D. Friedmann-Morvinski , E. A. Bushong , E. Ke , Y. Soda , T. Marumoto
关键词:
摘要: Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain tumor in humans. Here we show that gliomas can originate from differentiated cells in the …
sciencemag.org
unirioja.es
harvard.edu参考文章(34)
Karlyne M. Reilly, Dagan A. Loisel, Roderick T. Bronson, Margaret E. McLaughlin, Tyler Jacks, Nf1 ; Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects Nature Genetics. ,vol. 26, pp. 109- 113 ,(2000) , 10.1038/79075
Pascal Gagneux, Monica Cheriyan, Nancy Hurtado-Ziola, Els C. M. Brinkman van der Linden, Dan Anderson, Harold McClure, Ajit Varki, Nissi M. Varki, Human-specific Regulation of α2–6-linked Sialic Acids Journal of Biological Chemistry. ,vol. 278, pp. 48245- 48250 ,(2003) , 10.1074/JBC.M309813200
S. K. CHOW, H. HAKOZAKI, D. L. PRICE, N. A. B. MACLEAN, T. J. DEERINCK, J. C. BOUWER, M. E. MARTONE, S. T. PELTIER, M. H. ELLISMAN, Automated microscopy system for mosaic acquisition and processing Journal of Microscopy. ,vol. 222, pp. 76- 84 ,(2006) , 10.1111/J.1365-2818.2006.01577.X
N Lindberg, M Kastemar, T Olofsson, A Smits, L Uhrbom, Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma. Oncogene. ,vol. 28, pp. 2266- 2275 ,(2009) , 10.1038/ONC.2009.76
Diana L. Price, Sunny K. Chow, Natalie A. B. MacLean, Hiroyuki Hakozaki, Steve Peltier, Maryann E. Martone, Mark H. Ellisman, High-resolution large-scale mosaic imaging using multiphoton microscopy to characterize transgenic mouse models of human neurological disorders. Neuroinformatics. ,vol. 4, pp. 65- 80 ,(2006) , 10.1385/NI:4:1:65
Masahito Ikawa, Nobushige Tanaka, Winston W.-Y Kao, Inder M Verma, Generation of transgenic mice using lentiviral vectors: a novel preclinical assessment of lentiviral vectors for gene therapy Molecular Therapy. ,vol. 8, pp. 666- 673 ,(2003) , 10.1016/S1525-0016(03)00240-5
F. H. Gage, P. W. Coates, T. D. Palmer, H. G. Kuhn, L. J. Fisher, J. O. Suhonen, D. A. Peterson, S. T. Suhr, J. Ray, Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 11879- 11883 ,(1995) , 10.1073/PNAS.92.25.11879
Angelo L. Vescovi, Rossella Galli, Brent A. Reynolds, Brain tumour stem cells Nature Reviews Cancer. ,vol. 6, pp. 425- 436 ,(2006) , 10.1038/NRC1889
Yuan Zhu, Mario I Romero, Pritam Ghosh, Zhengyi Ye, Patrick Charnay, Elizabeth J Rushing, Jamey D Marth, Luis F Parada, Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain Genes & Development. ,vol. 15, pp. 859- 876 ,(2001) , 10.1101/GAD.862101
Jianwei Jiao, Dong Feng Chen, Induction of Neurogenesis in Nonconventional Neurogenic Regions of the Adult Central Nervous System by Niche Astrocyte-Produced Signals Stem Cells. ,vol. 26, pp. 1221- 1230 ,(2008) , 10.1634/STEMCELLS.2007-0513