Focus on the tumour periphery in MRI evaluation of soft tissue sarcoma: infiltrative growth signifies poor prognosis.
作者： Josefin Fernebro , Marie Wiklund , Kjell Jonsson , Pär-Ola Bendahl , Anders Rydholm
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摘要: Purpose. Infiltrative microscopical peripheral growth of soft tissue sarcomas (STS) has been shown to be prognostic importance and preoperative risk stratification could individualize neoadjuvant treatment. Patients methods. We assessed tumour pattern on MRI from 78 STS. The findings were correlated histopathology outcome. Results. MRI-based was classified as pushing in 34 tumours, focally infiltrative 25, diffusely 19. All tumours with diffuse infiltration also showed infiltration, whereas failed identify two-thirds the microscopically tumours. Diffusely gave a 2.5 times increased metastases (P = .01) 3.7 higher local recurrence .02). Discussion. Based this observation we suggest that evaluation STS should focus since it adds information value for decisions therapies.
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