作者: Steven L. Percival , David W. Williams
DOI: 10.1016/B978-0-12-397043-5.00012-8
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摘要: Endotracheal (ET) tubes are essential devices for maintaining the airway in mechanically ventilated patients and facilitating gaseous exchange. However, during use they can provide a surface development of biofilms, which contain potentially pathogenic micro-organisms. These micro-organisms may disseminate into patient’s lower airway, leading to ventilator-associated pneumonia (VAP). VAP significantly increases morbidity rate length patient stay intensive care. Evidence suggests that an improved understanding composition ET biofilm communities result preventative strategies VAP—in particular, impregnated with antimicrobials.