The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes.

作者: Elango Bhakkiyalakshmi , Dornadula Sireesh , Palanisamy Rajaguru , Ramasamy Paulmurugan , Kunka Mohanram Ramkumar

DOI: 10.1016/J.PHRS.2014.10.004

关键词:

摘要: … [141] identified Nrf2-mediated antioxidant defense through PI3K and ERK activation in human mammary epithelial cells exposed to EGCG. Moreover, EGCG supplementation was …

参考文章(149)
Weimin Sun, Wei Wang, Jung Kim, Peter Keng, Shanmin Yang, Hengshan Zhang, Chaomei Liu, Paul Okunieff, Lurong Zhang, Anti-cancer effect of resveratrol is associated with induction of apoptosis via a mitochondrial pathway alignment. Advances in Experimental Medicine and Biology. ,vol. 614, pp. 179- 186 ,(2008) , 10.1007/978-0-387-74911-2_21
Elango Bhakkiyalakshmi, Devibalan Shalini, Thillai Veerapazham Sekar, Palanisamy Rajaguru, Ramasamy Paulmurugan, Kunka Mohanram Ramkumar, Therapeutic potential of pterostilbene against pancreatic beta‐cell apoptosis mediated through Nrf2 British Journal of Pharmacology. ,vol. 171, pp. 1747- 1757 ,(2014) , 10.1111/BPH.12577
C. Roland Wolf, Ken Itoh, Colin J. Henderson, Masayuki Yamamoto, Simon A. Chanas, Michael McMahon, Christophe Cavin, Lesley I. McLellan, John D. Hayes, The Cap ‘n’ Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and Inducible Expression of Intestinal Detoxification and Glutathione Biosynthetic Enzymes Cancer Research. ,vol. 61, pp. 3299- 3307 ,(2001)
James D. Johnson, Dan S. Luciani, Mechanisms of Pancreatic β-Cell Apoptosis in Diabetes and Its Therapies Advances in Experimental Medicine and Biology. ,vol. 654, pp. 447- 462 ,(2010) , 10.1007/978-90-481-3271-3_19
Albena T Dinkova-Kostova, Jed W Fahey, Paul Talalay, Chemical Structures of Inducers of Nicotinamide Quinone Oxidoreductase 1 (NQO1) Methods in Enzymology. ,vol. 382, pp. 423- 448 ,(2004) , 10.1016/S0076-6879(04)82023-8
Sivakumar J. T. Gowder, H. Devaraj, Effect of the food flavour cinnamaldehyde on the antioxidant status of rat kidney. Basic & Clinical Pharmacology & Toxicology. ,vol. 99, pp. 379- 382 ,(2006) , 10.1111/J.1742-7843.2006.PTO_560.X
Sung Hee Kim, Sun Hee Hyun, Se Young Choung, Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice. Journal of Ethnopharmacology. ,vol. 104, pp. 119- 123 ,(2006) , 10.1016/J.JEP.2005.08.059
Michael B. Sporn, Karen T. Liby, Mark M. Yore, Liangfeng Fu, Justin M. Lopchuk, Gordon W. Gribble, New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress. Journal of Natural Products. ,vol. 74, pp. 537- 545 ,(2011) , 10.1021/NP100826Q
Albena T. Dinkova-Kostova, W. David Holtzclaw, Nobunao Wakabayashi, Keap1, the Sensor for Electrophiles and Oxidants that Regulates the Phase 2 Response, Is a Zinc Metalloprotein† Biochemistry. ,vol. 44, pp. 6889- 6899 ,(2005) , 10.1021/BI047434H