Tissue-specific role of Nrf2 in the treatment of diabetic foot ulcers during hyperbaric oxygen therapy.
Umapathy Dhamodharan , Amin Karan , Dornadula Sireesh , Alladi Vaishnavi
Free Radical Biology and Medicine 138 53 -62
12
2019
Targeting SUMOylation Cascade for Diabetes Management
Dornadula Sireesh , Elango Bhakkiyalakshmi , Kunka Ramkumar , Shanmugakani Rathinakumar
Current Drug Targets 15 ( 12) 1094 -1106
16
2014
Pterostilbene-mediated Nrf2 activation: Mechanistic insights on Keap1:Nrf2 interface.
Elango Bhakkiyalakshmi , Kesavan Dineshkumar , Suresh Karthik , Dornadula Sireesh
Bioorganic & Medicinal Chemistry 24 ( 16) 3378 -3386
34
2016
Gymnema montanum improves endothelial function via inhibition of endoplasmic reticulum stress by activating Nrf2 signaling
KunkaMohanram Ramkumar , Dornadula Sireesh , Natarajan Suganya , Suvro Chatterjee
Asian pacific Journal of Tropical Biomedicine 10 ( 8) 379
1
2020
Redox Sensitive Transcription via Nrf2-Keap1 in Suppression of Inflammation
Elango Bhakkiyalakshmi , Dornadula Sireesh , Kunka M. Ramkumar
Immunity and Inflammation in Health and Disease#R##N#Emerging Roles of Nutraceuticals and Functional Foods in Immune Support 149 -161
2
2018
Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade.
Dornadula Sireesh , Munuswamy-Ramanujam Ganesh , Umapathy Dhamodharan , Murugesan Sakthivadivel
Journal of Nutritional Biochemistry 44 ( 44) 11 -21
30
2017
Establishment of pancreatic microenvironment model of ER stress: Quercetin attenuates β-cell apoptosis by invoking nitric oxide-cGMP signaling in endothelial cells.
Natarajan Suganya , Krishna Priya Mani , Dornadula Sireesh , Palanisamy Rajaguru
Journal of Nutritional Biochemistry 55 142 -156
11
2018
Carvacrol induces mitochondria-mediated apoptosis in HL-60 promyelocytic and Jurkat T lymphoma cells.
Elango Bhakkiyalakshmi , Natarajan Suganya , Dornadula Sireesh , Kannan Krishnamurthi
European Journal of Pharmacology 772 92 -98
18
2016
Anti-hyperlipidemic and anti-peroxidative role of pterostilbene via Nrf2 signaling in experimental diabetes.
Elango Bhakkiyalakshmi , Dornadula Sireesh , Murugesan Sakthivadivel , Srinivasan Sivasubramanian
European Journal of Pharmacology 777 9 -16
61
2016
The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes.
Elango Bhakkiyalakshmi , Dornadula Sireesh , Palanisamy Rajaguru , Ramasamy Paulmurugan
Pharmacological Research 91 104 -114
135
2015
Unraveling the role of ER stress inhibitors in the context of metabolic diseases
Chodisetty Sarvani , Dornadula Sireesh , Kunka Mohanram Ramkumar
Pharmacological Research 119 412 -421
51
2017
Association of single-nucleotide polymorphisms of the KEAP1 gene with the risk of various human diseases and its functional impact using in silico analysis.
Umapathy Dhamodharan , Balashanmugam Ponjayanthi , Dornadula Sireesh , Elango Bhakkiyalakshmi
Pharmacological Research 137 205 -218
3
2018
Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
Dornadula Sireesh , Umapathy Dhamodharan , Krishnamoorthy Ezhilarasi , Viswanathan Vijay
Scientific Reports 8 ( 1) 5126 -5126
40
2018
Treatment With Naringenin Elevates the Activity of Transcription Factor Nrf2 to Protect Pancreatic β-Cells From Streptozotocin-Induced Diabetes in vitro and in vivo.
Rashmi Rajappa , Dornadula Sireesh , Magesh B. Salai , Kunka M. Ramkumar
Frontiers in Pharmacology 9 1562
42
2019
Association of A1538G and C2437T single nucleotide polymorphisms in heat shock protein-70 genes with diabetic nephropathy among South Indian population
Umapathy Dhamodharan , Krishnamoorthy Ezhilarasi , Balashanmugam Ponjayanthi , Dornadula Sireesh
Bioscience Reports 37 ( 2)
11
2017
Role of Redox Responsive Transcription Factor Nuclear Factor Erythroid 2 Related Factor 2 Nrf2 In Diabetes
Dornadula Sireesh
Kattankulathur
33-LB: Nuclear Factor Erythroid 2 Related Factor 2 (Nrf2) Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers
DHAMODHARAN UMAPATHY , POOJA VIKRAMAN , VAISHNAVI ALLADI , SOMASUNDAR ARUMUGAM
Diabetes 68
2019
Pathophysiological insights of methylglyoxal induced type-2 diabetes.
Sireesh Dornadula , Bhakkiyalakshmi Elango , Ponjayanthi Balashanmugam , Rajaguru Palanisamy
Chemical Research in Toxicology 28 ( 9) 1666 -1674
20
2015
Pterostilbene Ameliorates Streptozotocin-Induced Diabetes through Enhancing Antioxidant Signaling Pathways Mediated by Nrf2
Bhakkiyalakshmi Elango , Sireesh Dornadula , Ramasamy Paulmurugan , Kunka Mohanram Ramkumar
Chemical Research in Toxicology 29 ( 1) 47 -57
64
2016
The Nitrated Fatty Acid 10-Nitro-Oleate Attenuates Allergic Airway Disease
Aravind T. Reddy , Sowmya P. Lakshmi , Sireesh Dornadula , Sudheer Pinni
Journal of Immunology 191 ( 5) 2053 -2063
30
2013