Increased soluble markers of endothelial dysfunction in HIV-positive patients under highly active antiretroviral therapy.
作者： Katleen de Gaetano Donati , Ricardo Rabagliati , Mario Tumbarello , Evelina Tacconelli , Concetta Amore
DOI: 10.1097/00002030-200303280-00020
关键词:
摘要: Higher levels of soluble adhesion molecules have been found before the introduction highly active antiretroviral therapy (HAART) in HIV-positive compared with HIV-negative patients. To evaluate impact HAART on endothelial function we measured plasmatic concentrations 120 Concentrations P-selectin and fibrinolytic factors were significantly higher patients, whereas intercellular molecule-1 did not differ significantly. may induce an activation both directly indirectly through lipid alterations.
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