Detection of Plaque-Forming Cells in the Peripheral Blood of Actively Immunized Humans

摘要: Ten adult human volunteers were immunized with Salmonella typhi and their peripheral blood leukocytes collected for 14 days after immunization. These leukocytes, rich in lymphocytes, plaqued a modified Jerne assay against sheep erythrocytes coated either or Escherichia lipopolysaccharide. A specific direct indirect PFC response developed individuals by day 7 peaked at 10. This vigorous rapidly declined to normal levels 14. marked of may be as useful tool monitoring the humoral immune patients Gram-negative bacterial infections.