Comparative Developmental Toxicity and Stress Protein Responses of Dimethyl Sulfoxide to Rare Minnow and Zebrafish Embryos/Larvae.
作者： Xiaoqin Xiong , Si Luo , Benli Wu , Jianwei Wang
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摘要: Abstract Dimethyl sulfoxide (DMSO), a widely used carrier solvent, can be toxic to test organisms and has species-specific sensitivity. In this study, the developmental toxicity stress protein responses of DMSO rare minnow (Gobiocypris rarus) zebrafish (Danio rerio) with two tests were compared in early life stage. first test, fertilized eggs exposed 0%, 0.0001%, 0.001%, 0.01%, 0.1%, 1.0%, 1.5%, 2.0% v/v until 3 days post hatching. second larvae from 0 8 d 2% 4 days. Our results showed that was on multiple indexes, no-observed-effect concentrations both species 1.0% 0.001% for analysis analysis, respectively. Furthermore, more sensitive than spinal malformation. The period induction malformation by 0–7 d after hatch (dah) minno...
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