Removal of prostaglandin E2 and increased intraoperative blood pressure during modified ultrafiltration in pediatric cardiac surgery.

摘要: Objective We investigated the relationship between serum prostaglandin E 2 and intraoperative blood pressure in pediatric cardiac surgery with modified ultrafiltration. Methods In 35 consecutive patients (31.6 ± 26.8 months, 0.4–111 10.9 5.5 kg, 2.9–23.8 kg) who underwent ultrafiltration, we measured changes effluent , assessed hemodynamic parameters, performed subset analyses to compare low ( 10 n = 10) weights. Results During cardiopulmonary bypass, systolic decreased from 80.8 15.2 60.5 11.3 mm Hg P .00000002979) increased 16.6 8.7 58.8 53.3 pg/mL .002). although central venous catecholamine dosage transited at same levels, 83.4 14.1 21.1 11.6 .001), negative correlation R −0.392, .0000277723) 15,700 10,700 pg (1790 2230 pg/kg) removed during Decrease was significantly higher low-weight (51.8 58.4 pg/mL) than high-weight (15.7 30.1 pg/mL). Conclusion Removal of is one reason for effect more marked patients.