Local blood flow in Walker 256 metastatic brain tumors

摘要: Local blood flow (F) in metastatic Walker 256 (WL-256) brain tumors produced by the intracarotid artery injection of WL-256 tumor cells rats was measured using 14C-odoantipyrine and quantitative autoradiography. Blood variable tumors; overall range 2 to 222 ml hg−1 min−1 maximum an individual extended over 150 min−1. Small had mean flows similar surrounding brain. Medium large significantly lower flows; lowest values were usually necrotic or cystic regions, although low (less than 20 hg−1) also some viable-appearing regions. reduced adjacent medium but not small tumors. A global depression two animals with hydrocephalus largest burden. The patterns model are uniquely different from other models differences exist.