DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A

作者: Y. Liu , A. Rusinol , M. Sinensky , Y. Wang , Y. Zou

DOI: 10.1242/JCS.03263

关键词:

摘要: The genetic diseases Hutchinson-Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) arise from accumulation of farnesylated prelamin A because of defects in the lamin …

参考文章(36)
Yves Pommier, Kurt W. Kohn, Tsunehiro Shimizu, Chun-Xia Cao, Rong-Guang Shao, Patrick M. O'Connor, Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function Cancer Research. ,vol. 57, pp. 4029- 4035 ,(1997)
Maria Eriksson, W. Ted Brown, Leslie B. Gordon, Michael W. Glynn, Joel Singer, Laura Scott, Michael R. Erdos, Christiane M. Robbins, Tracy Y. Moses, Peter Berglund, Amalia Dutra, Evgenia Pak, Sandra Durkin, Antonei B. Csoka, Michael Boehnke, Thomas W. Glover, Francis S. Collins, Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome Nature. ,vol. 423, pp. 293- 298 ,(2003) , 10.1038/NATURE01629
David Cortez, Saritha Guntuku, Jun Qin, Stephen J Elledge, ATR and ATRIP: Partners in Checkpoint Signaling Science. ,vol. 294, pp. 1713- 1716 ,(2001) , 10.1126/SCIENCE.1065521
Fabrizio d'Adda di Fagagna, Philip M. Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas von Zglinicki, Gabriele Saretzki, Nigel P. Carter, Stephen P. Jackson, A DNA damage checkpoint response in telomere-initiated senescence Nature. ,vol. 426, pp. 194- 198 ,(2003) , 10.1038/NATURE02118
Tom Misteli, Paola Scaffidi, Genome instability in progeria: when repair gets old. Nature Medicine. ,vol. 11, pp. 718- 719 ,(2005) , 10.1038/NM0705-718
Clare H McGowan, Paul Russell, The DNA damage response: sensing and signaling Current Opinion in Cell Biology. ,vol. 16, pp. 629- 633 ,(2004) , 10.1016/J.CEB.2004.09.005
Ignacio Varela, Juan Cadiñanos, Alberto M. Pendás, Ana Gutiérrez-Fernández, Alicia R. Folgueras, Luis M. Sánchez, Zhongjun Zhou, Francisco J. Rodríguez, Colin L. Stewart, José A Vega, Karl Tryggvason, José M. P. Freije, Carlos López-Otín, Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation Nature. ,vol. 437, pp. 564- 568 ,(2005) , 10.1038/NATURE04019
T. von Zglinicki, G. Saretzki, J. Ladhoff, F. d’Adda di Fagagna, S.P. Jackson, Human cell senescence as a DNA damage response Mechanisms of Ageing and Development. ,vol. 126, pp. 111- 117 ,(2005) , 10.1016/J.MAD.2004.09.034
David B. Lombard, Katrin F. Chua, Raul Mostoslavsky, Sonia Franco, Monica Gostissa, Frederick W. Alt, DNA Repair, Genome Stability, and Aging Cell. ,vol. 120, pp. 497- 512 ,(2005) , 10.1016/J.CELL.2005.01.028