Persistent γH2AX: A promising molecular marker of DNA damage and aging.
作者： Mohammad Sabbir Siddiqui , Maxime François , Michael F. Fenech , Wayne R. Leifert
DOI: 10.1016/J.MRREV.2015.07.001
关键词:
摘要: … damage progressively increases with age and may contribute to or be caused by these accelerated aging … of γH2AX, in human aging and diseases of accelerated aging. The aims of this …
core.ac.uk
sci-hub.se 
researchgate.net 参考文章(186)
Melvin Lee Kiang Chua, Navita Somaiah, Roger A’Hern, Sue Davies, Lone Gothard, John Yarnold, Kai Rothkamm, Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy Radiotherapy and Oncology. ,vol. 99, pp. 362- 366 ,(2011) , 10.1016/J.RADONC.2011.05.071
Andrew Baschnagel, Andrea Russo, William E. Burgan, Donna Carter, Katie Beam, Diane Palmieri, Patricia S. Steeg, Philip Tofilon, Kevin Camphausen, Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts Molecular Cancer Therapeutics. ,vol. 8, pp. 1589- 1595 ,(2009) , 10.1158/1535-7163.MCT-09-0038
Darryl Hudson, Igor Kovalchuk, Igor Koturbash, Bryan Kolb, Olga A. Martin, Olga Kovalchuk, Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals Aging. ,vol. 3, pp. 609- 620 ,(2011) , 10.18632/AGING.100340
P.-O. Mari, B. I. Florea, S. P. Persengiev, N. S. Verkaik, H. T. Bruggenwirth, M. Modesti, G. Giglia-Mari, K. Bezstarosti, J. A. A. Demmers, T. M. Luider, A. B. Houtsmuller, D. C. van Gent, Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4 Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 18597- 18602 ,(2006) , 10.1073/PNAS.0609061103
Irina A. Zalenskaya, E.Morton Bradbury, Andrei O. Zalensky, Chromatin structure of telomere domain in human sperm. Biochemical and Biophysical Research Communications. ,vol. 279, pp. 213- 218 ,(2000) , 10.1006/BBRC.2000.3917
Dipanjan Chowdhury, Michael-Christopher Keogh, Haruhiko Ishii, Craig L. Peterson, Stephen Buratowski, Judy Lieberman, γ-H2AX Dephosphorylation by Protein Phosphatase 2A Facilitates DNA Double-Strand Break Repair Molecular Cell. ,vol. 20, pp. 801- 809 ,(2005) , 10.1016/J.MOLCEL.2005.10.003
Y. Liu, A. Rusinol, M. Sinensky, Y. Wang, Y. Zou, DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A Journal of Cell Science. ,vol. 119, pp. 4644- 4649 ,(2006) , 10.1242/JCS.03263
Tom Stiff, Mark O’Driscoll, Nicole Rief, Kuniyoshi Iwabuchi, Markus Löbrich, Penny A. Jeggo, ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Research. ,vol. 64, pp. 2390- 2396 ,(2004) , 10.1158/0008-5472.CAN-03-3207
Olga A. Sedelnikova, Izumi Horikawa, Christophe Redon, Asako Nakamura, Drazen B. Zimonjic, Nicholas C. Popescu, William M. Bonner, Delayed kinetics of DNA double-strand break processing in normal and pathological aging. Aging Cell. ,vol. 7, pp. 89- 100 ,(2008) , 10.1111/J.1474-9726.2007.00354.X
R. A. Kleinerman, A. A. Romanyukha, D. A. Schauer, J. D. Tucker, Retrospective assessment of radiation exposure using biological dosimetry: chromosome painting, electron paramagnetic resonance and the glycophorin a mutation assay. Radiation Research. ,vol. 166, pp. 287- 302 ,(2006) , 10.1667/RR3273.1