Treatment of Patients with a History of Recurrent Tonsillitis Due to Group A Beta-hemolytic Streptococci

摘要: Forty-five patients with a history of recurrent tonsillitis associated Group A beta-hemolytic streptococcal (GABHS) infection participated in prospective, randomized study comparing penicillin, erythromycin, or clindamycin therapy. Surface tonsillar cultures were obtained before therapy, 10 days after termination and once month for period 12 to 18 months. The specimens processed aerobic anaerobic bacteria. Beta lactamase-producing bacteria present 43 the 45 (96%) cultures. GABHS colonization was eradicated two 15 treated six 14 clindamycin. In long-term follow-up, eight one (p less than 0.0001 when compared penicillin p = 0.002 erythromycin) continued suffer from tonsillitis.