The MRC OX-44 antigen marks a functionally relevant subset among rat thymocytes.
作者： D J Paterson , J R Green , W A Jefferies , M Puklavec , A F Williams
DOI: 10.1084/JEM.165.1.1
关键词:
摘要: A monoclonal antibody called MRC OX-44 is described that labels all myeloid cells and peripheral lymphoid but only 12% of thymocytes. The OX-44+ thymic include most if not found in the medulla a small fraction cortical cells. Together with CD4 CD8 antigens, seven subsets cell were defined it was notable CD4- CD8- whereas almost CD4+ CD8+ OX-44-. In functional tests, accounted for proliferation by thymocytes when stimulated allogeneic spleen or concanavalin plus growth factors OX-44- completely negative these assays. Also, tests thymopoiesis after intra-thymic injection cells, activity OX-44+. It seems possible set may functionally relevant rat thymus.
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