Design, synthesis, and application of a Protein A mimetic

作者: Rongxiu Li , Victor Dowd , David J. Stewart , Stephen J. Burton , Christopher R. Lowe

DOI: 10.1038/NBT0298-190

关键词:

摘要: … We have developed a nonpeptidyl mimic for Staphylococcus aureus Protein A (SpA). The … for developing affinity ligands via a combination of computer-aided molecular design and …

参考文章(34)
Miguel AJ Godfrey, Piotr Kwasowski, Roland Clift, Vincent Marks, None, Assessment of the suitability of commercially available SpA affinity solid phases for the purificaion of murine monoclonal antibodies at process scale Journal of Immunological Methods. ,vol. 160, pp. 97- 105 ,(1993) , 10.1016/0022-1759(93)90013-W
Makonnen Belew, Nils Juntti, Anders Larsson, Jerker Porath, A one-step purification method for monoclonal antibodies based on salt-promoted adsorption chromatography on a 'thiophilic' adsorbent. Journal of Immunological Methods. ,vol. 102, pp. 173- 182 ,(1987) , 10.1016/0022-1759(87)90074-3
I. D. Kuntz, Structure-based strategies for drug design and discovery. Science. ,vol. 257, pp. 1078- 1082 ,(1992) , 10.1126/SCIENCE.257.5073.1078
L.L. Green, M.C. Hardy, C.E. Maynard-Currie, H. Tsuda, D.M. Louie, M.J. Mendez, H. Abderrahim, M. Noguchi, D.H. Smith, Y. Zeng, N.E. David, H. Sasai, D. Garza, D.G. Brenner, J.F. Hales, R.P. McGuinness, D.J. Capon, S. Klapholz, A. Jakobovits, Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs Nature Genetics. ,vol. 7, pp. 13- 21 ,(1994) , 10.1038/NG0594-13
Nils Lonberg, Lisa D Taylor, Fiona A Harding, Mary Trounstine, Kay M Higgins, Stephen R Schramm, Chiung-Chi Kuo, Roshanak Mashayekh, Kathryn Wymore, James G McCabe, Donna Munoz-O'Regan, Susan L O'Donnell, Elizabeth SG Lapachet, Tasha Bengoechea, Dianne M Fishwild, Condie E Carmack, Robert M Kay, Dennis Huszar, None, Antigen-specific human antibodies from mice comprising four distinct genetic modifications Nature. ,vol. 368, pp. 856- 859 ,(1994) , 10.1038/368856A0
Malcolm W. MacArthur, Paul C. Driscoll, Janet M. Thornton, NMR and crystallography — complementary approaches to structure determination Trends in Biotechnology. ,vol. 12, pp. 149- 153 ,(1994) , 10.1016/0167-7799(94)90074-4
Sten Ohlson, Rune Nilsson, Ulf Niss, Britt-Marie Kjellberg, Christian Freiburghaus, A novel approach to monoclonal antibody separation using high performance liquid affinity chromatography (HPLAC) with SelectiSpher-10 protein G Journal of Immunological Methods. ,vol. 114, pp. 175- 180 ,(1988) , 10.1016/0022-1759(88)90170-6
G. KÖHLER, C. MILSTEIN, Continuous cultures of fused cells secreting antibody of predefined specificity Nature. ,vol. 256, pp. 495- 497 ,(1975) , 10.1038/256495A0
William R. Taylor, Remotely related sequences and structures: Analysis and predictive modelling Trends in Biotechnology. ,vol. 12, pp. 154- 158 ,(1994) , 10.1016/0167-7799(94)90075-2