Pool sizes of the precursors for phosphatidylcholine synthesis in developing rat lung.
作者： Sonya Tokmakjian , Fred Possmayer
DOI: 10.1016/0005-2760(81)90103-X
关键词:
摘要: 1. Pulmonary maturation in the rat is accompanied by a 30% postnatal increase pool size of choline, 4-fold overall prenatal and decrease level cholinephosphate, 3-fold CDPcholine levels 2-fold content phosphatidylcholine. 2. The 1,2-diacyl-sn-glycerol lung increases 5-fold during fetal neonatal periods. Only minor alterations were noted fatty acid composition. 3. These results are consistent with an relative rates cholinephosphate cytidylyl-transferase cholinephosphotransferase steps phosphatidylcholine production pulmonary maturation. rate step catalyzed phosphatidate phosphohydrolase may also be increased.
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